The UK has developed a five year plan to reduce antimicrobial resistance “UK Five year antimicrobial resistance strategy”. The UK government commitment to taking action arose from the UK’s presidency of the G8 in 2013. This in turn had been propelled up the national agenda by the 2011 annual report of the CMO entitled “Infections and the Rise of Antimicrobial Resistance”. The plan runs from 2013 to 2018 so is now just over half way through its period of implementation. The strategy is designed to take a “one health approach” and therefore integrates veterinary and agricultural policy equally with human health. Seven key areas for future action were identified, (i)improving infection prevention (ii) optimising prescribing, (iii) improving education/public engagement, (iv) developing new drugs, (v) better surveillance, (vi) prioritisation AMR research, (vii) international collaboration. The strategy identified both existing and proposed actions to achieve a reduction in the amount of AMR seen in both humans and animals. Progress made in these areas will be discussed. A progress report has been published in 2014 jointly by the Department of Health and Department of Food and Rural Affairs, and this will be discussed. The successes and barriers to implementation of the strategy will also be discussed in the presentation.