Rice has been a staple food source for more than three billion people worldwide, however, rice is vulnerable to diseases. The most destructive disease of rice is rice blast and it is caused by a filamentous ascomycete fungus known as Magnaporthe oryzae (anamorph Pyricularia oryzae). This fungus attacks rice plants at all stages of development and causes annual losses of approximately 10%-30% in different countries. Fungicides are often used to control plant diseases, but people are concerns towards the use of fungicides as some of them have previously caused serious environmental and health problems. Hence, there are growing interest in discovering and developing new, improved fungicides as well as introducing alternative measures such as the use of biocontrol agents to manage plant diseases. Generally, biocontrol of rice blast disease is environmentally friendly and low cost. Streptomyces bacteria are well known for their ability to produce various bioactive compounds with antibacterial, antifungal, anticancer, antiviral, antioxidant, and immunosuppressive properties. In agricultural field, Streptomyces species have shown to possess biocontrol potential against a wide range of phytopathogenic fungi. This review project provides insight into the biocontrol potential of Streptomyces against rice blast fungus, Magnaporthe oryzae. Studies on the biocontrol of rice blast disease by different Streptomyces spp. have been carried out by several researchers under laboratory conditions and greenhouse/growth chamber conditions. Studies have proven that Streptomyces exhibited in vitro inhibitory activity against M. oryzae. In greenhouse, infected rice seedlings that treated with Streptomyces resulted in up to 88.3% disease reduction of rice blast. Streptomyces spp. are potential biocontrol agents that can be explored to provide effective control of rice blast disease. Nevertheless, further studies on the isolation, formulation and application methods of these useful Streptomyces as well as field experiments are required in order to establish excellent biocontrol agents.